About miRNALoc
MicroRNAs (miRNAs) are a class of non-coding RNA that are ~20-22 nucleotides long, act as a master regulator of gene expression through translational repression and/or degradation of targeted mRNAs in plants and animals. The distributions of miRISC (canonical and noncanonical forms) deduce the fact that different subcellular locations are required for the processing and degradation of miRNA itself or its targets. Identifying the whereabouts of miRNAs potentially informs miRNA functions. We have developed this server for predicting eight different subcellular localizations of miRNAs i.e., axon, cytoplasm, circulating, exosome, extracellular vesicle, microvesicle, mitochondrion and nucleus.
Please Cite:
Meher, P. K., Satpathy, S., & Rao, A. R. (2020). miRNALoc: predicting miRNA subcellular localizations based on principal component scores of physico-chemical properties and pseudo compositions of di-nucleotides. Scientific Reports, 10(1), 1-12.