Niyati Rai
Reaserch Associate
rainiyati@iasri.res.in, rainiyati.bioinfo@gmail.com

Citations and H index

Qualification

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• M.Sc. in Bioinformatics

Project

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• Centre for Agricultural Bioinformatics (CABin) Scheme (since March, 2015)
• Modelling, Pharmacophore based Virtual Screening of compounds and Docking Studies.
• Study of synonymous codon usage in the genome of Salinibacter ruber.
• Comparison of mitochondrial genome on the basis of ribosomal protein.

Research Interest

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• Structural Bioinformatics
• Computer Aided Drug Designing
• Genomics

Workshop Attended

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• Attended Workshop on "Structural Bioinformatics Approaches in Drug Discovery" 11th-12th November, 2014 at CSIR-CDRI Lucknow.

Important Publications

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• Md. Samir Farooqi, Mishra D. C., Niyati Rai, DP Singh, Anil Rai, Chaturvedi, K.K., Ratna Prabha and Manjeet Kaur (2016). Genome-wide relative analysis of codon usage bias and codon context pattern in the bacteria Salinibacter ruber, Chromohalobacter salexigens and Rhizobium etli. in Biochemistry and Analytical Biochemistry. 5:257. doi:10.4172/2161-1009.1000257.

• Khanam T, Shukla A, Rai Niyati and Ramachandran R. , Critical Determinants for Substrate Recognition and Catalysis in the M. tuberculosis Class II AP-endonuclease/3'-5' Exonuclease III (2015). BBA - Proteins and Proteomics 1854(5): 505-516.

• Chatterjee A, Pandey S, Singh P, Pathak N, Rai Niyati, Ramchandran R, Tripathi R, Srivastava K. Comparative functional efficacy of tyrosine phosphatases from pathogenic and non-pathogenic mycobacteria: Identification of specific phenyl cyclopropyl methyl-/ phenyl butenylazoles as potent inhibitors (2015). Applied Microbiology and Biotechnology, DOI 10.1007/s00253-015-6502-8.

• Yadav GP, Shree S,  Maurya R,  Rai Niyati, Singh DK, Srivastava KK and Ramachandran R. Characterization of M. tuberculosis SerB2, an Essential HAD-Family Phosphatase, Reveals Novel Properties (2014). PLOS ONE, 9(12): e115409.

• Anand N, Ramkrishnan G.R., Chaturvedi V, Singh S, Srivastva K.K, Sharma P, Rai Niyati, Ramachandran R, Dwivedi A.K., Gupta V, Pandey S, Kumar,  Shukla P.K., Pandey S.K., lal J, Tripathi R.P Identification of 1-[(4-Benzyloxyphenyl)-but-3-enyl]-1H-azoles as New class of Antitubercular Agents (2013). ACS Medicinal Chemistry Letters, 4: 958-963.

• Sanjukta RK, Farooqi MS, Sharma N, Rai Niyati, Mishra DC, Rai A, Singh DP and Chaturvedi KK. Statistical Analysis of codon usage in extremely halophilic bacterium, Salinibacter ruber DSM 13855 (2013). Online Journal of Bioinformatics, 14: 15-31.

• Sanjukta RK, Farooqi MS, Rai Niyati, Rai A, Sharma N, Mishra DC and Singh DP. Expression Analysis of Genes Responsible for Amino Acid Biosynthesis in Salinibacter ruber (2013). Indian Journal of Biochemistry & Biophysics, 50: 177-185.

Poster Presentation

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• Rai Niyati, Khanam T and Ramchandran R. Homology Modeling and DNA-protein binding studies of XthA classII AP endonuclease from M. tuberculosis. 43rd National seminar on crystallography, CSIR-Central Drug Research Institute, Lucknow 12th - 6th November, 2014, Page-65.

Conference Abstract

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• Singh P, Rai Niyati, Gupta S, Tripathi AK, Jain SK, Ramachandran R & Tripathi RK. Interactions of the XR108 motif with D125 in HIV-1 nef is important for oligomeric association and MHC-I downregulation. 5th International Symposium on Drug Development for Orphan/Neglected Diseases, CTDDR, 26th -28th February, 2013.

• Rai A, Farooqi MS, Sanjukta RK, Rai Niyati , Sharma N and Mishra DC. Assessment of codon usage bias in salt-stressed, Salinibacter ruber. 52nd Annual conference of AMI-2011-International Conference on Microbial Biotechnology for Sustainable Development, Panjab University, Chandigarh 3rd - 6th  November, 2011, Page-387.