Sudhir Srivastava
Dr. Sudhir Srivastava
Senior Scientist
sudhir.srivastava@icar.gov.in, sudhir0401bm@gmail.com
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Citations and H index



Research Interest


  • Bioinformatics
  • Computational Biology
  • Statistical Aspects of Proteomics and Genomics

Teaching


  • Chemoinformatics and IPR Issues
  • Bio-molecular Modelling and Simulation

Important Projects


  • Development of statistical and computational approach for preprocessing and analyzing high-throughput proteomics data with missing values. as PI

  • Methodology for Trait Specific Genes Identification as Co-PI

  • Methodology for Protein Structure Comparison and its Web Implementation (institute funded project) as PI

  • A New Distributed Computing Framework for Data Mining (DIT funded project) as Co-investigator with Birla Institute of Technology and Science (BITS), Pilani as the Leading Institute

  • Development of a Tool for Comparison of Protein 3D Structure using Graph Theoretic Approach (institute funded project) as Co-PI

  • Multilabel Functional Classification of Abiotic Stress Related Proteins in Poaceae (institute funded project) as Co-PI


Important Publications


  • Ahlawat, S., Arora, R., Sharma, R., Chhabra, P., Kumar, A., Kaur, M., Lal, S.B., Mishra, D.C., Farooqi, M.S. and Srivastava, S. (2023). Revelation of genes associated with energy generating metabolic pathways in the fighter type Aseel chicken of India through skeletal muscle transcriptome sequencing. Animal Biotechnology iconpdf

  • Arora, R., Sharma, R., Ahlawat, S., Chhabra, P., Kumar, A., Kaur, M., Vijh, R.K., Lal, S.B., Mishra, D.C., Farooqi, M.S., and Srivastava, S.(2023). Transcriptomics reveals key genes responsible for functional diversity in pectoralis major muscles of native black Kadaknath and broiler chicken. 3 Biotech, 13, 253. iconpdf

  • Kumar, M., Ansari, W.A,. Zeyad, M.T. Singh, A., Chakdar, H., Kumar, A., Farooqi, M.S., Sharma, A., Srivastava, S., and Kumar. A.(2023) Core microbiota of wheat rhizosphere under Upper Indo-Gangetic plains and their response to soil physicochemical properties, Frontiers in Plant Science,VOLUME 14 iconpdf

  • Mir, Z.A., Chauhan, D., Pradhan, A.K., Srivastava, S., V., Sharma, D., Budhlakoti, N., Mishra, D.C., Jadon, V., Sahu, T. K., Grover, M., Gangwar, O.P., Kumar, S., Bhardwaj, S.C., Padaria, J.C., Singh, A.K., Rai, A., Singh G. P., Kumar, S. (2023). Comparative transcriptome profiling of near isogenic lines PBW343 and FLW29 to unravel defense related genes and pathways contributing to stripe rust resistance in wheat. Funct Integr Genomics, 23(2), 1-19. iconpdf

  • Singh, D. P., Bisen, M. S., Prabha, R., Maurya, S., Yerasu, S. R., Shukla, R., Tiwari, J. K., Chaturvedi, K. K., Farooqi, Md. S., Srivastava, S., Rai, A., Sarma, B. K., Rai, N., Singh, P. M., Behera, T. K., & Farag, M. A. (2023). Untargeted Metabolomics of Alternaria solani-Challenged Wild Tomato Species Solanum cheesmaniae Revealed Key Metabolite Biomarkers and Insight into Altered Metabolic Pathways. Metabolites, 13(5), 585. iconpdf

  • Srivastava, S., Merchant, M., McClain J. Craig, Rai, A., Chaturvedi, K.K., Angadi, U.B., Mishra, C.D. and Rai N. Shesh* (2023). Advanced Multivariable Statistical Analysis Interactive Tool for Handling Missing Data and Confounding Covariates for Label-free LC-MS Proteomics Experiments, Current Bioinformatics,18(5).. iconpdf

  • Sharma, R., Arora, R., Ahlawat, S., Chhabra, P., Kumar, A., Kaur, M., Lal, S. B., Mishra, D. C., Farooqi, M. S., & Srivastava, S. (2023). Study on the muscle transcriptome of two diverse Indian backyard poultry breeds acclimatized to different agro-ecological conditions. Molecular biology reports, 10.1007/s11033-022-08223-1. Advance online publication. iconpdf

  • Budhlakoti, N., Mishra, D.C., Majumdar, S.G., Kumar, A., Srivastava, S., Rai, S.N. and Rai, A. Integrated Model for Genomic Prediction under Additive and Non-Additive Genetic Architecture. Frontiers in Plant Science, 13:1027558. iconpdf

  • Mishra, D.C., Arora, D., Budhlakoti, N., Solanke, A.U., Mithra, S., Kumar, A., Pandey, P.S., Srivastava, S., Kumar, S., Farooqi, M.S., Lal, S.B., Rai, A., & Chaturvedi, K.K. (2022). Identification of Potential Cytokinin Responsive Key Genes in Rice Treated With Trans-Zeatin Through Systems Biology Approach. Frontiers in genetics, 12, 780599.iconpdf

  • Banerjee, M., Al-Eryani, L., Srivastava, S., Rai, S.N. , Pan, J., Kalbfleisch, T.S., States, J.C. Delineating the Effects of Passaging and Exposure in a Longitudinal Study of Arsenic-Induced Squamous Cell Carcinoma in a HaCaT Cell Line Model. Toxicol Sci. 2021 Nov 3 iconpdf

  • Jin, J., Wahlang, B. , Thapa, M., Head, K.Z., Hardesty, J.E. , Srivastava, S., Merchant, M.L. , Rai, S.N., Prough, R.A., and Cave, M.C.(2021). Proteomics and Metabolic Phenotyping Define Principal Roles for the Aryl Hydrocarbon Receptor in Mouse Liver, Acta Pharmaceutica Sinica B. iconpdf

  • Banerjee, M., Cardoso, A.F., Al-Eryani, L., Pan, J., Kalbfleisch, T.S., Srivastava, S., Rai S.N., & Christopher, J. States (2021). Dynamic alteration in miRNA and mRNA expression profiles at different stages of chronic arsenic exposure-induced carcinogenesis in a human cell culture model of skin cancer. Archives of Toxicology. iconpdf

  • O'Brien S.J., Kalbflesich T., Srivastava, S., Pan J., Rai S., Petras R.E., Ronquillo N., Polk H.C. Jr, Galandiuk S. (2021). Decreased Tumoral Expression of Colon-Specific Water Channel Aquaporin 8 Is Associated With Reduced Overall Survival in Colon Adenocarcinoma. Diseases of the Colon and Rectum. iconpdf

  • O'Brien S., Fiechter, C. Burton, J., Hallion, J. Paas, M., Patel, Ankur, Patel, Ajay, Rochet, A., Scheurlen, K., Gardner, S., Eichenberger, M., Sarojini, S., Srivastava, S., Rai, S.N., Kalbfleisch, T., Polk, H.J. and Galandiuk, S. (2021). Long non-coding RNA ZFAS1 is a major regulator of epithelial-mesenchymal transition through miR-200/ZEB1/E-cadherin, Vimentin signaling in colon adenocarcinoma. Cell Death Discovery, 7, 61. iconpdf

  • Veda Krishnan, Monika Awana, A. P. Raja Rani, Navita Bansal, Haritha Bollinedi, Sudhir Srivastava, Susheel Sharma, Ashok Kumar Singh, Archana Singh, Shelly Praveen. (Published on October 6, 2020). Quality matrix reveals the potential of Chak-hao as a nutritional supplement: A comparative study of matrix components, antioxidants and physico-chemical attributes, Journal of Food Measurement and Characterization.[IF (2019): 1.648]iconpdf

  • Veda Krishnan, Debarati Mondal, Haritha Bollinedi, Sudhir Srivastava, Ramesh SV, Latha Madhavan, Archana Singh, A.K. Singh, Shelly Praveen (2020). Cooking fat types alter the inherent glycaemic response of niche rice varieties through resistant starch (RS) formation, International Journal of Biological Macromolecules, 162, 1668-1681.[IF (2020): 5.162]iconpdf

  • Jin, J., Wahlang, B., Shi, H., Hardesty, J.E.., Falkner, K.C., Head, K.Z.,Srivastava, S, Merchant, M.L., Rai, S.N., Cave, M.C. and Prough, R.A. (2020). Dioxin-like and non-dioxin-like PCBs differentially regulate the hepatic proteome and modify diet-induced nonalcoholic fatty liver disease severity, Medicinal Chemistry Research, 29, 1247–1263.[IF: 1.783 (2019)].iconpdf

  • Krishnan, V., Rani, R., Pushkar, S., Lal, S.K., Srivastava, S., Kumari, S., Vinutha, T., Dahuja, A., Praveen, S. & Sachdev, A. (March 19, 2020). Anthocyanin fingerprinting and dynamics in differentially pigmented exotic soybean genotypes using modified HPLC–DAD method, Journal of Food Measurement and Characterization.iconpdf

  • U. B. Angadi, K. K. Chaturvedi, Srivastava, S. and Rai Anil. "A Novel Way of Comparing Protein 3D Structure Using Graph Partitioning Approach," in IEEE/ACM Transactions on Computational Biology and Bioinformatics.iconpdf

  • Rai, S.N., Srivastava, S., Pan, J., Wu, X., Rai, S.P., Mekmaysy, C.S., DeLeeuw, L., Chaires, J.B., Garbett, N.C (2019). Multi-group diagnostic classification of high-dimensional data using differential scanning calorimetry plasma thermograms. PLOS ONE 14(8): e0220765. iconpdf

  • Monendra Grover, Dwijesh C. Mishra, Naveen Sharma, Sudhir Srivastava, Anil Rai (2017) The maximum computational capacity of proteins involved in abiotic stress differs significantly from the proteins not involved in abiotic stress, National Academy Science Letters, (), 1-3, 10.1007/s40009-017-0557-2.

  • Srivastava, S, Lal, SB, Mishra, DC, Angadi,UB, Chaturvedi, KK, Rai, SN and Rai, A (2016). An efficient algorithm for protein structure comparison using elastic shape analysis. Algorithms for Molecular Biology, 11, 27, DOI: 10.1186/s13015-016-0089-1.

  • Anu Sharma, S. B. Lal, D. C. Mishra, Sudhir Srivastava and Anil Rai (2013). A web Based Software for Synonymous Codon Usage Indices. International Journal of Information and Computation Technology, 3(3): 147-152.

  • Sudhir Srivastava, Cini Varghese, Seema Jaggi and Eldho Varghese (2013). Diallel cross designs for test versus control comparisons. The Indian Journal of Genetics and Plant Breeding,, 73(2), 186-193.


  • Sudhir Srivastava, Cini Varghese, Seema Jaggi and Eldho Varghese(2015). Augmented partial diallel cross plans involving two sets of parental lines.. The Indian Journal of Genetics and Plant Breeding,75 (1), 105-109.



  • Book Chapter:


  • D.C. Mishra, Sanjeev Kumar, Anil Rai, Sudhir Srivastava (2013). Machine Learning Techniques and Its Application in Bioinformatics. Information and Knowledge Management: Tools, Techniques and Practices, pp: 155-168. Publisher: New India Publishing Agency.


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