Dr. Sunil Kumar
Dr. Sunil Kumar
Principal Scientist
sunil.kumar7@icar.gov.in, skybiotech@gmail.com
Citations and H index

Area of Interest

  • Mainly focus on proteins with regard to their structures, functions, mutations and interactions.
  • Bioinformatics and Proteomics of Agricultural related problem.
  • Metagenomics and NGS.
  • Plant Microbe Interactions.

Important Projects

  • In Sillico exploration of the feasiblilty of Curcumin for the management of Phytophthora infestans.

  • Computational biology approach for deciphering stress induced transcriptomic and proteomic changes in rice-microbial interaction system

  • Structure prediction, Molecular Dyanamics stimulations of endopolygalacturonase and its interaction with PGIP (polygalacturonase-inhibiting protein)

  • Design of Novel small molecule mimics binding to quorum sensors in Ralstonia Solanacearum

  • Metatranscriptomics and metaproteomics analysis of wheat rhizosphere

Foreign Visit

  • Malaysia
  • Singapore
  • Switzerland

Awards and Honours

  • Department of Biotechnology (DBT), Government of India nominated for participation in Indo-Malaysia Bilateral workshop and International Conference from 2-11 September, 2003 in Malaysia
  • Awarded travel support by Department of Biotechnology (DBT), Government of India to attend 8th International Conference on Bioinformatics (InCoB 2009) from 7-11 September 2009 in Singapore.
  • Awarded travel support by Department of Science & Technology (DST), Government of India to attend 8th Europeanl Conference on Computational Biology (ECCB) from 9-12 September 2012 in Basel, Switzerland.
  • Distinguished Scientist Award: by the society for Bioinformatics and Biological Sciences, Allahabad for the year 2015.
  • Fellow: Society of Applied Biotechnology (2016)
  • Fellow: Association of Biotechnology and Pharmacy(2016).
  • Best poster Award: 03
  • Best Paper Award: 01

Important Publications(last five years)

  • Tiwari, D., Murmu, S., Indari, O., Jha, H.C., Kumar S.(2022) Targeting Epstein-Barr virus dUTPase, an immunomodulatory protein using anti-viral, anti-inflammatory and neuroprotective phytochemicals. Chem Biodivers ;19(9):e202200527. (IF:2.74; NAAS IF: 8.74) iconpdf

  • Kumar S., Ahmad K, Behera SK, Nagrale DT, Chaurasia A, Yadav MK, Murmu S, Jha Y, Rajawat MVS, Malviya D, Singh UB, Shankar R, Tripathy M, Singh HV (2022). Biocomputational Assessment of Natural Compounds as a Potent Inhibitor to Quorum Sensors in Ralstonia solanacearum. Molecules. 27(9):3034.. PMID: 35566383; (IF: 4.45; NAAS: 10.45).iconpdf

  • Girdhar, K., Thakur, S., Gaur, P., Choubey, A., Dogra, S., Dehury, B., Kumar S., Biswas, B., Dwivedi, D.K., Ghosh, S., Mondal, P. (2022) Design, synthesis, and biological evaluation of a small molecule oral agonist of the glucagon-like-peptide-1 receptor. J Biol Chem. 101889. PMID: 35378127. (IF 5.15) iconpdf

  • Mahata, S., Behera, S.K., Kumar S., Sahoo, P.K., Sarkar, S., Fazil, MHUT, Nasare, V.D. In-silico and in-vitro investigation of STAT3-PIM1 heterodimeric complex: Its mechanism and inhibition by curcumin for cancer therapeutics. Int J Biol Macromol. iconpdf

  • Yadav, M.K., Ahmad, S., Raza, K., Kumar S., Eswaran, M., Pasha, Km.M. Predictive modeling and therapeutic repurposing of natural compounds against the receptor-binding domain of SARS-CoV-2. J Biomol Struct Dyn. 2022 Jan 3:1-13. iconpdf

  • Jaiswal, S., Jaisri J., Kumari, J., Iquebal, M.A., Gujjar, A.K.S., Nayan, V., Angadi, U.B., Kumar S., Kumar, R., Datta, T.K., Rai, A., Kumar, D. (2021). Genome wide prediction, mapping and development of genomic resources of Mastitis associated genes in Buffalo. Frontiers in Veterinary Sciences. iconpdf

  • Choudhary P., Bhowmik A., Chakdar H., Khan M.A., Selvaraj C., Singh S.K., Kumar M., Kumar S., Saxena A.K. (2020) Understanding the biological role of PqqB in Pseudomonas stutzeri using molecular dynamics simulation approach; J Biomol Struct Dyn; 8;1-13. iconpdf

  • Mishra P, Paital B, Jena S, Swain SS, Kumar S, Yadav MK, Chainy GBN, SamantaL(2019) Possible activation of NRF2 by Vitamin E/Curcumin against altered thyroid hormone inducedoxidative stress via NFĸB/AKT/mTOR/KEAP1 signalling in rat heart. Sci Rep. 9(1):7408.iconpdf

  • Singh UB, Malviya D, Singh S, Kumar M, Sahu PK, Singh HV, Kumar S, Roy M, Imran M, Rai JP, Sharma AK, Saxena AK (2019) Trichoderma harzianum- and Methyl Jasmonate-Induced Resistance to Bipolaris sorokiniana Through Enhanced Phenylpropanoid Activities in Bread Wheat (Triticum aestivum L.); Front Microbiol. 2019 Jul 31;10:1697. iconpdf

  • Ashutosh Kumar, Dinesh K. Agarwal, Sunil Kumar, Y. Mohan Reddy, Anjani Devi Chintagunta, K.V. Saritha, Govind Pal, S.P. Jeevan Kumar (2019) Nutraceuticals derived from seed storage proteins: Implications for health wellness, Biocatalysis and Agricultural Biotechnology;17: 710-719. iconpdf

  • Prassan Choudhary, Hillol Chakdar, Arjun Singh, Sunil Kumar, Sanjeev Kumar Singh, Murali Aarthy, Sanjay Kumar Goswami, Alok Kumar Srivastava & Anil Kumar Saxena (2019) Computational identification and antifungal bioassay reveals phytosterols as potential inhibitor of Alternaria arborescens, Journal of Biomolecular Structure and Dynamics.iconpdf

  • Singh UB, Singh S, Malviya D, Karthikeyan N, Imran M, Chaurasia R, Alam M, Singh P, Sarma BK, Rai JP, Damodaran T, Tripathi JK, Kumar S & Sharma AK (2019) Integration of anti-penetrant tricyclazole, signaling molecule salicylic acid and root associated Pseudomonas fluorescens enhances suppression of Bipolaris sorokiniana in bread wheat (Triticum aestivum L.) Journal of Plant Pathology. iconpdf

  • Sunil Kumar, MHU Turabe Fazil, Khursheed Ahmad, Minaketan Tripathy, and Navin Kumar Verma (2019) Computational Analysis of Protein-Protein Interactions in Motile T-cells; Methods in Molecular Biology; 2019;1930:149-156. iconpdf

  • Chik MW, Hussain Z, Zulkefeli M, Tripathy M, Kumar S, Majeed ABA, Byrappa K (2019) Polymer-wrapped single walled carbon nanotubes: : transformation toward better applications in healthcare. Drug Deliv Transl Res. 2018. doi: 10.1007/s13346-018-0505-9. (IF: 3.2; NAAS: 9.2) iconpdf

  • Girdhar K, Dehury B, Singh MK, Daniel VP, Choubey A, Dogra S, Kumar S, Mondal P. (2018) Novel insights into the dynamics behavior of Glucagon-Like Peptide-1 Receptor with its small molecule Agonists; J Biomol Struct Dyn. 2018 Nov 17:1-11. iconpdf

  • Sunil Kumar, Khurshid Ahmad, Gitanjali Tandon, Udai B. Singh, Yachana Jha, Dipak T. Nagrale, Mahender Kumar Singh, Khyati Girdhar, Prosenjit Mondal (2018) Novel insight into the molecular interaction of catalase and sucrose: A combination of in silico and in planta assays study. Computers and Electronics in Agriculture 151: 258-263. iconpdf

  • Vemulawada Chakrapani, Kiran D. Rasal, Sunil Kumar, Shibani Mohapatra, Jitendra K. Sundaray, Pallipuram Jayasankar and Hirak K. Barman (2017) In silico analysis of nsSNPs of carp TLR22 gene affecting its structural stability and binding ability with poly I:C; Interdisciplinary Sciences: Computational Life Sciences.iconpdf

  • Verma NK, Fazil MH, Ong ST, Chalasani ML, Low JH, Kottaiswamy A, P P, Kizhakeyil A, Kumar S, Panda AK, Freeley M, Smith SM, Boehm BO, Kelleher D (2016) LFA-1/ICAM-1 ligation in T-cells promotes Th1 polarization through a GSK3β signalling-dependent Notch pathway; J Immunol. 2016 Jul 1;197(1):108-18. iconpdf

  • Radin Nur Afiqah, Biswaranjan Paital, Sunil Kumar, Abu Bakar Abdul Majeed, Minaketan Tripathy (2016) AgNO3 Dependant Modulation of Glucose Mediated Respiration Kinetics in Escherichia coli at Different pH and Temperature. Journal of Molecular Recognition; 29(11):544-554, iconpdf

  • Iquebal MA, Jaiswal S, Angadi UB, Sablok G, Arora V, Kumar S, Rai A and Kumar D (2015) SBMDb: First whole genome microsatellite DNA marker database of sugarbeet for bioenergy and industrial applications" Database (Oxford). 2015 Dec 8;2015. pii: bav111. iconpdf

  • Biswaranjan Paital, Sunil kumar*, Gaurav sablok, Sanjeev kumar Singh and GBN Chainy (2016) Investigating the conformational structure and potential site interactions of SOD inhibitors on Ec-SOD in marine mud crab Scylla serrata: A molecular modeling approach” “Interdisciplinary Sciences: Computational Life Sciences”. 8: 312. iconpdf

  • Yachana Jha, Gaurav Sablok, Naidu Subbarao, Raja Sudhakar, MHU Turabe Fazil, R B Subramanian, Andrea Squartini, Sunil Kumar* (2014) Bacterial-induced expression of RAB18 protein in Orzya sativa salinity stress and insights into molecular interaction with GTP ligand. Journal of Molecular Recognition; 27(9):521-7.iconpdf

  • Gitanjali Tandon, Sarika, M.A. Iquebal, Sunil Kumar, Sukhdeep Kaur, Anil Rai and Dinesh Kumar (2015) Evidence of salicylic acid pathway with EDS1 and PAD4 proteins by molecular dynamics simulation for Grape improvement; Journal of Biomolecular Structure and Dynamics, 33(10):2180-91 dx. iconpdf

  • Rawat R, Kumar S, Chadha BS, Kumar D, Oberoi HS. (2015) An acidothermophilic functionally active novel GH12 family endoglucanase from Aspergillus niger HO: purification, characterization and molecular interaction studies, Antonie van Leeuwenhoek, Journal of Microbiology; Jan2015, 107(1):103-17. iconpdf

  • Norhafiza Razali, Renu Agarwal, Puneet Agarwal, Sunil Kumar, Minaketan Tripathy , Sushil Vasudevan, Jonathan G Crowston and Nafeeza M Ismail (2015) Role of adenosine receptors in resveratrol-induced IOP lowering in rats with steroid-induced ocular hypertension. Clinical and Experimental Opthalmology; 43(1):54-66 ; iconpdf

Book Edited:

  • S Sablok, G., Kumar, S., Ueno, S., Kuo, J., Varotto, C. (Eds.) Advances in the Understanding of Biological Sciences Using Next Generation Sequencing (NGS) Approaches (Springer) ISBN 978-3-319-17156-2

Book /Manual Chapters

  • Jaiswal, S., Iquebal, M.A. , Angadi U.B. , Kumar, S., Rai, A., Singh, N.K., Kumar, D.(2021) Mango Genomic Resources and Databases. In: Kole C. (eds) The Mango Genome. Compendium of Plant Genomes. Springer, Cham. Book Chapter The Mango Genome pp 219-228,iconpdf

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